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Enhances your mind's potential

A safe and non addictive anxiolytic

Up to 50% of people around the world feel stressed at least 3 times a week. Conventional pharmaceutical anxiolytic molecules have been linked to undesirable side effects such as tolerance and dependency. Mistrusting those conventional medications, people experiencing medium stress symptoms are looking for safer solutions.

As the expert in mental balance solutions, GPE created SCUTELL’UP® an ingredient to improve mood without sedative effects.

SCUTELL’UP® is an extract from Scutellaria baicalensis rich in flavones with demonstrated anti-stress activities.


good reasons
to choose SCUTELL’UP®


Natural anti-stress
Without sedation

Immediate action

Results in 2 hours No rebound anxiety

No habituation

No rebound anxiety upon cessation


Full traceability control
No adverse effects
No addiction

Premium quality

Only the best raw material quality

A demonstrated biological activity

Decrease of stress hormone level

The level of Corticosterone, the stress hormone, is drastically increased upon a stress condition. In a chronic mild stress context, Scutellaria extract can reverse its effects, acting as efficiently as conventional medication (such as Fluoxetine).

Stress hormone level (ng/ml)
Stress hormone level (ng/ml)
  1. CMS
  2. CMS + Fluoxetine
  3. CMS + Scutellaria

Corticosterone level in plasma after 15 days of Chronic Mild Stress (CMS) in mice3

No cognitive or motor impairment

In addition, Baicalin, the main flavone present in Scutellaria Baicalensis extract, does not cause cognitive impairment or any motor incoordination effects, not even at high concentrations.

Step through latency(s)
Step through latency(s)
Baicalin exhibited no memory-impairing effects on mice in the step-through passive avoidance test as compared to diazepam8

No sedative effect

No rebound anxiety

Technical Data

Commercial name



Scutellaria baicalensis root extract

Active compounds

Baicalin: ≥ 85%



Recommended dosage

20 mg – 1 to 3 times/day
for a 3 to 6 weeks treatment or as needed


Food supplements: tablets, capsules, softgel capsules, sachets…
Liquid formulations


1. Pang et al. 2016, Multiple-Ascending-Dose Pharmacokinetics and Safety Evaluation of Baicalein Chewable Tablets in Healthy Chinese Volunteers, Clin Drug Investig 2. Brock et al. 2014, American Skullcap (Scutellaria lateriflora): A Randomised, Double-Blind Placebo-Controlled Crossover Study of its Effects on Mood in Healthy Volunteers, Phytother. Res 3. Pao et al. 2012, Three Chinese herbal medicines promote neuroproliferation in vitro, and reverse the effects of chronic mild stress on behavior, the HPA axis, and proliferation of hippocampal precursor cell in vivo, Journal of Ethnopharmacology 4. Zhou et al. 2019, Baicalin regulates the dopamine system to control the core symptoms of ADHD, Molecular Brain 5. Chang et al. 2011, Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep–wake regulation, Journal of Ethnopharmacology 6. Shin et al. 2014, Preventive effects of skullcap (Scutellaria baicalensis) extract in a mouse model of food allergy, Journal of Ethnopharmacology 7. Limanaqi, et al. 2020, « Potential Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea », Antioxidants 8. Wang et al. 2008, GABAA receptor subtype selectivity underlying selective anxiolytic effect of baicalin, Neuropharmacology