SAFFR'UP®
Restores Emotional Balance Naturally
Up to 50% of people worldwide report feeling stressed multiple times per week. As interest in mental well-being continues to grow, many are turning to natural ways to support a balanced mood and emotional resilience in everyday life.
SAFFR’UP®, a natural product based on the joint action of SAFFR’ACTIV® and SCUTELL’UP®, carefully selected and scientifically studied herbal extracts for their benefits in mental health.
A formula designed to restore emotional balance by naturally managing symptoms of anxiety and depression and improving emotional wellbeing.
Naturally Rooted in Tradition
Crocus sativus has a long history of use in traditional wellness practices. Today, its active compounds — including crocins and safranal — have been studied for their role in supporting mood and emotional balance1,2. Emerging research has also explored saffron’s potential link to sleep quality3, a key factor in managing stress and overall vitality.
Scutellaria baicalensis, commonly used in traditional herbal infusions, is rich in flavonoids studied for their potential to help promote calm and mental clarity. Research has also examined its role in supporting mood and everyday emotional stability4,5.
Clinically supported efficacy6
A randomized, double-blind, placebo-controlled clinical study conducted on 180 participants demonstrated a significant improvement in emotional well-being, including mood balance and reduced stress perception. SAFFR’UP®— a unique combination of Crocus sativus and Scutellaria baicalensis extracts — has been shown to support emotional resilience and contribute to a more positive mood. These results are backed by standardized assessment tools and ongoing scientific research. SAFFR’UP® offers a natural, well-tolerated solution for those seeking daily emotional balance.
Figure 1. V3 – V2 score differences
Figure 2. V3 – V2 score differences
Technical Data
Active compounds
Joint effect of saffron extract + Scutellaria baicalensis
Saffron extract: Crocins ≥ 3%, by UV&HPLC, Safranal ≥ 2% by UV
Baicalin: ≥ 85% HPLC
Recommended dosage
50 mg/day for a period of 4 to 6 weeks, as needed
Several possible galenic forms to bring a complete answer to customers
Powder for solid forms such as tablets, capsules or microcapsules
good reasons
to choose SAFFR’UP®
Proven Efficacy
Clinically-proven efficacy on emotional health
Quality Commitment
Safety
Full traceability control
No adverse effects
Innovation
Joint effect of 2 powerful actives
No dependency
Bibliography
1. Noorbala et al., Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial. Journal of Ethnopharmacology 97 (2005) 281–284.
2. Tabeshpour et al., A double-blind, randomized, placebo-controlled trial of saffron stigma (Crocus sativus L.) in mothers suffering from mild-to-moderate postpartum depression. Phytomedicine 36 (2017) 145–152.
3. Pachikian et al.,. Effects of Saffron Extract on Sleep Quality: A Randomized Double-Blind Controlled Clinical Trial. Nutrients (2021), 13, 1473.
4. Marques de Carvalho et al., Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice. Behavioural Brain Research 221 (2011) 75–82.
5. Liu et al., Anti-Depressive Effectiveness of Baicalin In Vitro and In Vivo. Molecules (2019), 24, 326.
6. Dormal et al., The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients, (2025), 17, 809.
